Publication: A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics
A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics
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Genov, N., Castellana, S., Scholkmann, F., Capocefalo, D., Truglio, M., Rosati, J., Turco, E. M., Biagini, T., Carbone, A., Mazza, T., Relógio, A., & Mazzoccoli, G. (2019). A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics. International Journal of Molecular Sciences, 20, 4585. https://doi.org/10.3390/ijms20184585
Abstract
Abstract
Abstract
Cellular, organ, and whole animal physiology show temporal variation predominantly featuring 24-h (circadian) periodicity. Time-course mRNA gene expression profiling in mouse liver showed two subsets of genes oscillating at the second (12-h) and third (8-h) harmonic of the prime (24-h) frequency. The aim of our study was to identify specific genomic, proteomic, and functional properties of ultradian and circadian subsets. We found hallmarks of the three oscillating gene subsets, including different (i) functional annotation, (ii) prot
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Creators (Authors)
- Genov, Nikolai
- Castellana, Stefano
- Scholkmann, Felix
- Capocefalo, Daniele
- Truglio, Mauro
- Rosati, Jessica
- Turco, Elisa Maria
- Biagini, Tommaso
- Carbone, Annalucia
- Mazza, Tommaso
- Relógio, Angela
- Mazzoccoli, Gianluigi
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Citations
Genov, N., Castellana, S., Scholkmann, F., Capocefalo, D., Truglio, M., Rosati, J., Turco, E. M., Biagini, T., Carbone, A., Mazza, T., Relógio, A., & Mazzoccoli, G. (2019). A Multi-Layered Study on Harmonic Oscillations in Mammalian Genomics and Proteomics. International Journal of Molecular Sciences, 20, 4585. https://doi.org/10.3390/ijms20184585
