Publication: The Binding Properties and Physiological Functions of Recoverin
The Binding Properties and Physiological Functions of Recoverin
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Zang, J., & Neuhauss, S. C. F. (2018). The Binding Properties and Physiological Functions of Recoverin. Frontiers in Molecular Neuroscience, 11, 473. https://doi.org/10.3389/fnmol.2018.00473
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Recoverin (Rcv) is a low molecular-weight, neuronal calcium sensor (NCS) primarily located in photoreceptor outer segments of the vertebrate retina. Calcium ions (Ca)-bound Rcv has been proposed to inhibit G-protein-coupled receptor kinase (GRKs) in darkness. During the light response, the Ca-free Rcv releases GRK, which in turn phosphorylates visual pigment, ultimately leading to the cessation of the visual transduction cascade. Technological advances over the last decade have contributed significantly to a deeper understanding of Rc
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Zang, J., & Neuhauss, S. C. F. (2018). The Binding Properties and Physiological Functions of Recoverin. Frontiers in Molecular Neuroscience, 11, 473. https://doi.org/10.3389/fnmol.2018.00473
