Publication: Identification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy - a before-after study
Identification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy - a before-after study
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Agnetti, J., Büchler, A. C., Osthoff, M., Helfenstein, F., Weisser, M., Siegemund, M., Bassetti, S., Bingisser, R., Schaefer, D. J., Clauss, M., Hinic, V., Tschudin-Sutter, S., Bättig, V., Khanna, N., & Egli, A. (2023). Identification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy - a before-after study. BMC Infectious Diseases, 23(1), 730. https://doi.org/10.1186/s12879-023-08732-9
Abstract
Abstract
Abstract
BACKGROUND
The BioFire® FilmArray® Blood Culture Identification Panel 1 (BF-FA-BCIP) detects microorganisms with high accuracy in positive blood cultures (BC) - a key step in the management of patients with suspected bacteraemia. We aimed to compare the time to optimal antimicrobial therapy (OAT) for the BF-FA-BCIP vs. standard culture-based identification.
METHODS
In this retrospective single-centre study with a before-after design, 386 positive BC cases with identification by BF-FA-BCIP were compared to 414 controls with culture-
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Creators (Authors)
- Agnetti, Jessica
- Büchler, Andrea C
- Osthoff, Michael
- Helfenstein, Fabrice
- Weisser, Maja
- Siegemund, Martin
- Bassetti, Stefano
- Bingisser, Roland
- Schaefer, Dirk J
- Clauss, Martin
- Hinic, Vladimira
- Tschudin-Sutter, Sarah
- Bättig, Veronika
- Khanna, Nina
- Egli, Adrian
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Citations
Agnetti, J., Büchler, A. C., Osthoff, M., Helfenstein, F., Weisser, M., Siegemund, M., Bassetti, S., Bingisser, R., Schaefer, D. J., Clauss, M., Hinic, V., Tschudin-Sutter, S., Bättig, V., Khanna, N., & Egli, A. (2023). Identification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy - a before-after study. BMC Infectious Diseases, 23(1), 730. https://doi.org/10.1186/s12879-023-08732-9
