Publication: Sleep homeostasis and models of sleep regulation.
Sleep homeostasis and models of sleep regulation.
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Borbély, A. A., & Achermann, P. (1999). Sleep homeostasis and models of sleep regulation. Journal of Biological Rhythms, 14, 557–568. https://doi.org/10.1177/074873099129000894
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According to the two-process model of sleep regulation, the timing and structure of sleep are determined by the interaction of a homeostatic and a circadian process. The original qualitative model was elaborated to quantitative versions that included the ultradian dynamics of sleep in relation to the non-REM-REM sleep cycle. The time course of EEG slow-wave activity, the major marker of non-REM sleep homeostasis, as well as daytime alertness were simulated successfully for a considerable number of experimental protocols. They include
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- Borbély, A A
- Achermann, P
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Borbély, A. A., & Achermann, P. (1999). Sleep homeostasis and models of sleep regulation. Journal of Biological Rhythms, 14, 557–568. https://doi.org/10.1177/074873099129000894