Publication: Targeting the host response in sepsis: current approaches and future evidence
Targeting the host response in sepsis: current approaches and future evidence
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Bode, C., Weis, S., Sauer, A., Wendel-Garcia, P., & David, S. (2023). Targeting the host response in sepsis: current approaches and future evidence. Critical Care, 27(1), 478. https://doi.org/10.1186/s13054-023-04762-6
Abstract
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Abstract
Sepsis, a dysregulated host response to infection characterized by organ failure, is one of the leading causes of death worldwide. Disbalances of the immune response play an important role in its pathophysiology. Patients may develop simultaneously or concomitantly states of systemic or local hyperinflammation and immunosuppression. Although a variety of effective immunomodulatory treatments are generally available, attempts to inhibit or stimulate the immune system in sepsis have failed so far to improve patients’ outcome. The underl
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- Bode, Christian
- Weis, Sebastian
- Sauer, Andrea
- Wendel-Garcia, Pedro
- David, Sascha
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Bode, C., Weis, S., Sauer, A., Wendel-Garcia, P., & David, S. (2023). Targeting the host response in sepsis: current approaches and future evidence. Critical Care, 27(1), 478. https://doi.org/10.1186/s13054-023-04762-6
