Publication: Enzyme mediated site-specific surface modification
Enzyme mediated site-specific surface modification
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Sala, A., Ehrbar, M., Trentin, D., Schoenmakers, R. G., Vörös, J., & Weber, F. E. (2010). Enzyme mediated site-specific surface modification. Langmuir, 26(13), 11127–11134. https://doi.org/10.1021/la1008895
Abstract
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Abstract
Stable tethering of bioactive peptides like RGD to surfaces can be achieved via chemical bonding, biotin streptavidin interaction, or photocross-linking. More challenging is the immobilization of proteins, since methods applied to immobilize peptides are either not specific or versatile enough or might even compromise the protein's bioactivity. To overcome this limitation, we have employed a scheme that by enzymatic (transglutaminase) reaction allows the site-directed and site-specific coupling of growth factors and other molecules to
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Creators (Authors)
- Sala, A
- Trentin, D
- Schoenmakers, R G
- Vörös, J
- Weber, Franz E
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Citations
Sala, A., Ehrbar, M., Trentin, D., Schoenmakers, R. G., Vörös, J., & Weber, F. E. (2010). Enzyme mediated site-specific surface modification. Langmuir, 26(13), 11127–11134. https://doi.org/10.1021/la1008895
