Publication: Amniotic fluid-derived mesenchymal stem cells lead to bone differentiation when cocultured with dental pulp stem cells
Amniotic fluid-derived mesenchymal stem cells lead to bone differentiation when cocultured with dental pulp stem cells
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De Rosa, A., Tirino, V., Paino, F., Tartaglione, A., Mitsiadis, T. A., Feki, A., d’Aquino, R., Laino, L., Colacurci, N., & Papaccio, G. (2011). Amniotic fluid-derived mesenchymal stem cells lead to bone differentiation when cocultured with dental pulp stem cells. Tissue Engineering. Part A, 17(5–6), 645–653. https://doi.org/10.1089/ten.tea.2010.0340
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Mesenchymal stem cells are present in many tissues of the human body, including amniotic fluid (AF) and dental pulp (DP). Stem cells of both AF and DP give rise to a variety of differentiated cells. In our experience, DP stem cells (DPSCs) display a high capacity to produce bone. Therefore, our aim was to investigate if AF-derived stem cells (AFSCs) were able to undergo bone differentiation in the presence of DPSCs. AFSCs were seeded under three different conditions: (i) cocultured with DPSCs previously differentiated into osteoblasts
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De Rosa, A., Tirino, V., Paino, F., Tartaglione, A., Mitsiadis, T. A., Feki, A., d’Aquino, R., Laino, L., Colacurci, N., & Papaccio, G. (2011). Amniotic fluid-derived mesenchymal stem cells lead to bone differentiation when cocultured with dental pulp stem cells. Tissue Engineering. Part A, 17(5–6), 645–653. https://doi.org/10.1089/ten.tea.2010.0340