Publication: Adaptive Image Segmentation Reveals Substantial Cortical Bone Remodeling During Early Fracture Repair
Adaptive Image Segmentation Reveals Substantial Cortical Bone Remodeling During Early Fracture Repair
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Ariyanfar, A., Klein, K., von Rechenberg, B., Darwiche, S., & Dailey, H. L. (2024). Adaptive Image Segmentation Reveals Substantial Cortical Bone Remodeling During Early Fracture Repair. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 12(1), 2345165. https://doi.org/10.1080/21681163.2024.2345165
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The goal of this study was to develop an image analysis algorithm for quantifying the effects of remodeling on cortical bone during early fracture healing. An adaptive thresholding technique with boundary curvature and tortuosity control was developed to automatically identify the endocortical and pericortical boundaries in the presence of high-gradient bone mineral density (BMD) near the healing zone. The algorithm successfully segmented more than 47,000 microCT images from 12 healing ovine osteotomies and intact contralateral tibiae
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Ariyanfar, A., Klein, K., von Rechenberg, B., Darwiche, S., & Dailey, H. L. (2024). Adaptive Image Segmentation Reveals Substantial Cortical Bone Remodeling During Early Fracture Repair. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 12(1), 2345165. https://doi.org/10.1080/21681163.2024.2345165