Publication: Pulp-derived exosomes in a fibrin-based regenerative root filling material
Pulp-derived exosomes in a fibrin-based regenerative root filling material
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Ivica, A., Ghayor, C., Zehnder, M., Valdec, S., & Weber, F. E. (2020). Pulp-derived exosomes in a fibrin-based regenerative root filling material. Journal of Clinical Medicine, 9(2), 491. https://doi.org/10.3390/jcm9020491
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Regenerative endodontics has been described as a paradigm shift in dentistry, despite its current limitation to immature teeth and reparative rather than regenerative outcomes. Cell-free treatments are favored because of regulatory issues. However, the recruitment of host-derived stem cells to the desired site remains challenging. We investigated whether dental pulp-derived exosomes, which are extracellular vesicles that contain proteins, lipids, RNA, and DNA and thus mirror their parental cells, may be used for this purpose. The use
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Ivica, A., Ghayor, C., Zehnder, M., Valdec, S., & Weber, F. E. (2020). Pulp-derived exosomes in a fibrin-based regenerative root filling material. Journal of Clinical Medicine, 9(2), 491. https://doi.org/10.3390/jcm9020491