Publication:

Association between prefrontal glutamine levels and neuroticism determined using proton magnetic resonance spectroscopy

Date

Date

Date
2019
Journal Article
Published version

Citations

Citation copied

Hasler, G., Buchmann, A., Haynes, M., Müller, S. T., Ghisleni, C., Brechbühl, S., & Tuura, R. (2019). Association between prefrontal glutamine levels and neuroticism determined using proton magnetic resonance spectroscopy. Translational Psychiatry, 9, 170. https://doi.org/10.1038/s41398-019-0500-z

Abstract

Abstract

Abstract

There is growing evidence for GABA and glutamate-glutamine dysfunction in the pathogenesis of mood and anxiety disorders. It is important to study this pathology in the early phases of the illness in order to develop new approaches to secondary prevention. New magnetic resonance spectroscopy (MRS) measures allow determining glutamine, the principal metabolite of synaptic glutamate that is directly related to glutamate levels in the synaptic cleft, as well as glutamate and GABA. In contrast to previous investigations, this study used c

Additional indexing

Creators (Authors)

  • Hasler, Gregor
    affiliation.icon.alt
  • Buchmann, Andreas
    affiliation.icon.alt
  • Haynes, Melanie
    affiliation.icon.alt
  • Müller, Sabrina Theresia
    affiliation.icon.alt
  • Ghisleni, Carmen
    affiliation.icon.alt
  • Brechbühl, Sarela
    affiliation.icon.alt
  • Tuura, Ruth
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
9

Number

Number

Number
1

Page range/Item number

Page range/Item number

Page range/Item number
170

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2019-06-18

Date available

Date available

Date available
2020-01-10

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2158-3188

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Hasler, G., Buchmann, A., Haynes, M., Müller, S. T., Ghisleni, C., Brechbühl, S., & Tuura, R. (2019). Association between prefrontal glutamine levels and neuroticism determined using proton magnetic resonance spectroscopy. Translational Psychiatry, 9, 170. https://doi.org/10.1038/s41398-019-0500-z

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