Publication: The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
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Ahmadov, U., Picard, D., Bartl, J., Silginer, M., et al, & Roth, P. (2021). The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma. Cell Death and Disease, 12(10), 885. https://doi.org/10.1038/s41419-021-04146-0
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Glioblastoma is the most common malignant primary brain tumor. To date, clinically relevant biomarkers are restricted to isocitrate dehydrogenase (IDH) gene 1 or 2 mutations and O6-methylguanine DNA methyltransferase (MGMT) promoter methylation. Long non-coding RNAs (lncRNAs) have been shown to contribute to glioblastoma pathogenesis and could potentially serve as novel biomarkers. The clinical significance of HOXA Transcript Antisense RNA, Myeloid-Specific 1 (HOTAIRM1) was determined by analyzing HOTAIRM1 in multiple glioblastoma gen
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- Ahmadov, Ulvi
- Picard, Daniel
- Bartl, Jasmin
- Silginer, Manuela
- Roth, Patrick
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Ahmadov, U., Picard, D., Bartl, J., Silginer, M., et al, & Roth, P. (2021). The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma. Cell Death and Disease, 12(10), 885. https://doi.org/10.1038/s41419-021-04146-0
