Publication: An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations
An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations
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Cozzolino, M., Ketteler, M., & Wagner, C. A. (2020). An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations. Expert Opinion on Therapeutic Targets, 24, 477–488. https://doi.org/10.1080/14728222.2020.1743680
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Introduction: The management of hyperphosphatemia in patients with chronic kidney disease (CKD) is complicated, requiring a multidisciplinary approach that includes dietary phosphate restriction, dialysis, and phosphate binders.Areas covered: We describe key players involved in regulating inorganic phosphate homeostasis and their differential role in healthy people and different stages of CKD. The contribution of paracellular and transcellular intestinal absorptive mechanisms are also examined. Finally, we illuminate recent therapeuti
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- Cozzolino, Mario
- Ketteler, Markus
- Wagner, Carsten Alexander
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Cozzolino, M., Ketteler, M., & Wagner, C. A. (2020). An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations. Expert Opinion on Therapeutic Targets, 24, 477–488. https://doi.org/10.1080/14728222.2020.1743680
