Publication: γ1 GABA$_{A}$Receptors in Spinal Nociceptive Circuits
γ1 GABA$_{A}$Receptors in Spinal Nociceptive Circuits
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Neumann, E., Cramer, T., Acuña, M. A., Scheurer, L., Beccarini, C., Luscher, B., Wildner, H., & Zeilhofer, H. U. (2024). γ1 GABA$_{A}$Receptors in Spinal Nociceptive Circuits. Journal of Neuroscience, 44(41), e0591242024. https://doi.org/10.1523/jneurosci.0591-24.2024
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GABAergic neurons and GABA${A}$receptors (GABA${A}$Rs) are critical elements of almost all neuronal circuits. Most GABA${A}$Rs of the CNS are heteropentameric ion channels composed of two α, two β, and one γ subunits. These receptors serve as important drug targets for benzodiazepine (BDZ) site agonists, which potentiate the action of GABA at GABA${A}$Rs. Most GABA$_{A}$
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Neumann, E., Cramer, T., Acuña, M. A., Scheurer, L., Beccarini, C., Luscher, B., Wildner, H., & Zeilhofer, H. U. (2024). γ1 GABA$_{A}$Receptors in Spinal Nociceptive Circuits. Journal of Neuroscience, 44(41), e0591242024. https://doi.org/10.1523/jneurosci.0591-24.2024