Publication: Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells
Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells
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Date
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Citations
Imesch, P., Scheiner, D., Szabo, E., Fink, D., & Fedier, A. (2013). Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells. Experimental and Therapeutic Medicine, 6(3), 786–790. https://doi.org/10.3892/etm.2013.1205
Abstract
Abstract
Abstract
Polycationic cell-penetrating peptides (CPPs) deliver macromolecules into cells without losing the functional properties of the cargoed macromolecule. The aim of this study was to determine whether exogenous cytochrome c is delivered to HeLa cervical carcinoma cells by the CPP antennapedia (Antp) and activates apoptosis. HeLa cervical carcinoma cells were treated with conjugated Antp-SMCC-cytochrome c (cytochrome c chemically conjugated to Antp) or with non-conjugated Antp and cytochrome c. Sensitivity to the treatments was determined
Additional indexing
Creators (Authors)
- Imesch, Patrick
- Scheiner, David
- Szabo, Emese
- Fink, Daniel
- Fedier, André
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Citations
Imesch, P., Scheiner, D., Szabo, E., Fink, D., & Fedier, A. (2013). Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells. Experimental and Therapeutic Medicine, 6(3), 786–790. https://doi.org/10.3892/etm.2013.1205
