Publication: Arterial lactate above 2 mM is associated with increased brain lactate and decreased brain glucose in patients with severe traumatic brain injury
Arterial lactate above 2 mM is associated with increased brain lactate and decreased brain glucose in patients with severe traumatic brain injury
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Meierhans, R., Brandi, G., Fasshauer, M., Sommerfeld, J., Schüpbach, R., Béchir, M., & Stover, J. (2012). Arterial lactate above 2 mM is associated with increased brain lactate and decreased brain glucose in patients with severe traumatic brain injury. Minerva Anestesiologica, 78(2), 185–193. http://www.minervamedica.it/en/journals/minerva-anestesiologica/article.php?cod=R02Y2012N02A0185
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BACKGROUND: Lactate fuels cerebral energy-consuming processes and it is neuroprotective. The impact of arterial lactate on brain metabolism determined by microdialysis was investigated retrospectively in patients with severe traumatic brain injury (TBI). METHODS: Cerebral microdialysis (glucose, lactate), neuromonitoring (ICP, CPP, ptiO2, SjvO2) and blood gas data collected in 20 patients during pharmacologic coma were grouped within predefined arterial lactate clusters (<1, 1-2, >2 mM). Microdialysis samples were only taken from time
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- Meierhans, Roman
- Brandi, Giovanna
- Fasshauer, Mario
- Sommerfeld, Jutta
- Schüpbach, Reto
- Béchir, Markus
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Meierhans, R., Brandi, G., Fasshauer, M., Sommerfeld, J., Schüpbach, R., Béchir, M., & Stover, J. (2012). Arterial lactate above 2 mM is associated with increased brain lactate and decreased brain glucose in patients with severe traumatic brain injury. Minerva Anestesiologica, 78(2), 185–193. http://www.minervamedica.it/en/journals/minerva-anestesiologica/article.php?cod=R02Y2012N02A0185
