Publication: Clinical Utility of Procalcitonin in the Diagnosis of Pneumonia
Clinical Utility of Procalcitonin in the Diagnosis of Pneumonia
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Wussler, D., Kozhuharov, N., Tavares Oliveira, M., Bossa, A., Sabti, Z., Nowak, A., Murray, K., du Fay de Lavallaz, J., Badertscher, P., Twerenbold, R., Shrestha, S., Flores, D., Nestelberger, T., Walter, J., Boeddinghaus, J., Zimmermann, T., Koechlin, L., von Eckardstein, A., Breidthardt, T., & Mueller, C. (2019). Clinical Utility of Procalcitonin in the Diagnosis of Pneumonia. Clinical Chemistry, 65(12), 1532–1542. https://doi.org/10.1373/clinchem.2019.306787
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BACKGROUND The clinical utility of procalcitonin in the diagnosis and management of pneumonia remains controversial. METHODS We assessed the clinical utility of procalcitonin in 2 prospective studies: first, a multicenter diagnostic study in patients presenting to the emergency department with acute dyspnea to directly compare the diagnostic accuracy of procalcitonin with that of interleukin 6 and C-reactive protein (CRP) in the diagnosis of pneumonia; second, a randomized management study of procalcitonin guidance in patients with ac
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Wussler, D., Kozhuharov, N., Tavares Oliveira, M., Bossa, A., Sabti, Z., Nowak, A., Murray, K., du Fay de Lavallaz, J., Badertscher, P., Twerenbold, R., Shrestha, S., Flores, D., Nestelberger, T., Walter, J., Boeddinghaus, J., Zimmermann, T., Koechlin, L., von Eckardstein, A., Breidthardt, T., & Mueller, C. (2019). Clinical Utility of Procalcitonin in the Diagnosis of Pneumonia. Clinical Chemistry, 65(12), 1532–1542. https://doi.org/10.1373/clinchem.2019.306787