Publication: Accelerated angiogenesis by continuous medium flow with vascular endothelial growth factor inside tissue-engineered trachea
Accelerated angiogenesis by continuous medium flow with vascular endothelial growth factor inside tissue-engineered trachea
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Tan, Q., Steiner, R., Yang, L., Welti, M., Neuenschwander, P., Hillinger, S., & Weder, W. (2007). Accelerated angiogenesis by continuous medium flow with vascular endothelial growth factor inside tissue-engineered trachea. European Journal of Cardio-Thoracic Surgery, 31, 806–811. https://doi.org/10.1016/j.ejcts.2007.01.045
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Objective: To test the effects of a continuous medium flow inside DegraPol® scaffolds on the reepithelialization and revascularization processes of a tissue-engineered trachea prosthesis. Methods: In this proof-of-principle study a continuous medium flow was maintained within a tubular DegraPol® scaffold by an inserted porous catheter connected to a pump system. The impact of the intra-scaffold medium flow on the survival of a tracheal epithelial sheet wrapped around and on chondrocyte delivery to the DegraPol® scaffold was studied. I
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Tan, Q., Steiner, R., Yang, L., Welti, M., Neuenschwander, P., Hillinger, S., & Weder, W. (2007). Accelerated angiogenesis by continuous medium flow with vascular endothelial growth factor inside tissue-engineered trachea. European Journal of Cardio-Thoracic Surgery, 31, 806–811. https://doi.org/10.1016/j.ejcts.2007.01.045