Publication: Intramyometrial and intravenous oxytocin compared to intravenous carbetocin for prevention of postpartum hemorrhage in elective cesarean section—A quasi‐randomized controlled phase IV non‐inferiority interventional trial
Intramyometrial and intravenous oxytocin compared to intravenous carbetocin for prevention of postpartum hemorrhage in elective cesarean section—A quasi‐randomized controlled phase IV non‐inferiority interventional trial
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Brun, R., Meier, L., Kapfhammer, E., Zimmermann, R., Ochsenbein‐Kölble, N., & Haslinger, C. (2024). Intramyometrial and intravenous oxytocin compared to intravenous carbetocin for prevention of postpartum hemorrhage in elective cesarean section—A quasi‐randomized controlled phase IV non‐inferiority interventional trial. Acta Obstetricia et Gynecologica Scandinavica, 103(9), 1838–1846. https://doi.org/10.1111/aogs.14893
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Introduction Our objective was to assess non‐inferiority of the unique approach used in our institution of combined 10 IU IM (intramyometrial) and 10 IU IV (intravenous) oxytocin to carbetocin IV in preventing severe postpartum blood loss in elective cesarean sections. The design was a prospective controlled phase IV non‐inferiority interventional trial. The setting was a tertiary center at University Hospital, Zurich, Switzerland.
Material and Methods The population consisted of 550 women undergoing elective cesarean section after 3
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Brun, R., Meier, L., Kapfhammer, E., Zimmermann, R., Ochsenbein‐Kölble, N., & Haslinger, C. (2024). Intramyometrial and intravenous oxytocin compared to intravenous carbetocin for prevention of postpartum hemorrhage in elective cesarean section—A quasi‐randomized controlled phase IV non‐inferiority interventional trial. Acta Obstetricia et Gynecologica Scandinavica, 103(9), 1838–1846. https://doi.org/10.1111/aogs.14893