Publication: The importance of murine cortical bone microstructure for microcrack initiation and propagation
The importance of murine cortical bone microstructure for microcrack initiation and propagation
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Voide, R., Schneider, P., Stauber, M., van Lenthe, G. H., Stampanoni, M., & Müller, R. (2011). The importance of murine cortical bone microstructure for microcrack initiation and propagation. Bone, 49(6), 1186–1193. https://doi.org/10.1016/j.bone.2011.08.011
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In order to better understand bone postyield behavior and consequently bone failure behavior, this study aimed first to investigate cortical bone microstructure and second, to relate cortical bone microstructure to microdamage initiation and propagation in C57BL/6 (B6) and C3H/He (C3H) mice; two murine inbred strains known for their differences in bone phenotype. Murine femora of B6 and C3H were loaded axially under compression in a stepwise manner. For each loading step, 3D data sets at a nominal resolution of 700 nm were acquired by
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Voide, R., Schneider, P., Stauber, M., van Lenthe, G. H., Stampanoni, M., & Müller, R. (2011). The importance of murine cortical bone microstructure for microcrack initiation and propagation. Bone, 49(6), 1186–1193. https://doi.org/10.1016/j.bone.2011.08.011