Publication: Molecular and cellular effects of chemicals disrupting steroidogenesis during early ovarian development of brown trout (Salmo trutta fario)
Molecular and cellular effects of chemicals disrupting steroidogenesis during early ovarian development of brown trout (Salmo trutta fario)
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a Marca Pereira, M. L., Eppler, E., Thorpe, K. L., Wheeler, J. R., & Burkhardt-Holm, P. (2014). Molecular and cellular effects of chemicals disrupting steroidogenesis during early ovarian development of brown trout (Salmo trutta fario). Environmental Toxicology, 29, 199–206. https://doi.org/10.1002/tox.20786
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A range of chemicals found in the aquatic environment have the potential to influence endocrine function and affect sexual development by mimicking or antagonizing the effects of hormones, or by altering the synthesis and metabolism of hormones. The aim of this study was to evaluate whether the effects of chemicals interfering with sex hormone synthesis may affect the regulation of early ovarian development via the modulation of sex steroid and insulin‐like growth factor (IGF) systems. To this end, ex vivo ovary cultures of juvenile b
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a Marca Pereira, M. L., Eppler, E., Thorpe, K. L., Wheeler, J. R., & Burkhardt-Holm, P. (2014). Molecular and cellular effects of chemicals disrupting steroidogenesis during early ovarian development of brown trout (Salmo trutta fario). Environmental Toxicology, 29, 199–206. https://doi.org/10.1002/tox.20786