Publication:

Nogo-A regulates vascular network architecture in the postnatal brain

Date

Date

Date
2017
Journal Article
Published version

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Wälchli, T., Ulmann-Schuler, A., Hintermüller, C., Meyer, E., Stampanoni, M., Carmeliet, P., Emmert, M. Y., Bozinov, O., Regli, L., Schwab, M. E., Vogel, J., & Hoerstrup, S. P. (2017). Nogo-A regulates vascular network architecture in the postnatal brain. Journal of Cerebral Blood Flow and Metabolism, 37(2), 614–631. https://doi.org/10.1177/0271678X16675182

Abstract

Abstract

Abstract

Recently, we discovered a new role for the well-known axonal growth inhibitory molecule Nogo-A as a negative regulator of angiogenesis in the developing central nervous system. However, how Nogo-A affected the three-dimensional (3D) central nervous system (CNS) vascular network architecture remained unknown. Here, using vascular corrosion casting, hierarchical, synchrotron radiation μCT-based network imaging and computer-aided network analysis, we found that genetic ablation of Nogo-A significantly increased the three-dimensional vasc

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144 since deposited on 2016-12-21
Acq. date: 2025-11-09

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Creators (Authors)

  • Wälchli, Thomas
    affiliation.icon.alt
  • Ulmann-Schuler, Alexandra
    affiliation.icon.alt
  • Hintermüller, Christoph
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  • Meyer, Eric
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  • Stampanoni, Marco
    affiliation.icon.alt
  • Carmeliet, Peter
    affiliation.icon.alt
  • Emmert, Maximilian Y
    affiliation.icon.alt
  • Bozinov, Oliver
    affiliation.icon.alt
  • Regli, Luca
    affiliation.icon.alt
  • Schwab, Martin E
    affiliation.icon.alt
  • Vogel, Johannes
    affiliation.icon.alt
  • Hoerstrup, Simon P
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
37

Number

Number

Number
2

Page Range

Page Range

Page Range
614

Page end

Page end

Page end
631

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2017

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Date available

Date available
2016-12-21

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Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0271-678X

OA Status

OA Status

OA Status
Closed

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DOI

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PubMed ID

PubMed ID

Metrics

Views

144 since deposited on 2016-12-21
Acq. date: 2025-11-09

Citations

Citation copied

Wälchli, T., Ulmann-Schuler, A., Hintermüller, C., Meyer, E., Stampanoni, M., Carmeliet, P., Emmert, M. Y., Bozinov, O., Regli, L., Schwab, M. E., Vogel, J., & Hoerstrup, S. P. (2017). Nogo-A regulates vascular network architecture in the postnatal brain. Journal of Cerebral Blood Flow and Metabolism, 37(2), 614–631. https://doi.org/10.1177/0271678X16675182

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