Publication: Normative modeling of brain morphometry in Clinical High-Risk for Psychosis
Normative modeling of brain morphometry in Clinical High-Risk for Psychosis
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Haas, S. S., Ge, R., Agartz, I., Amminger, G. P., Andreassen, O. A., Bachman, P., Baeza, I., Choi, S., Colibazzi, T., Cropley, V. L., de la Fuente-Sandoval, C., Ebdrup, B. H., Fortea, A., Fusar-Poli, P., Glenthøj, B. Y., Glenthøj, L. B., Haut, K. M., Hayes, R. A., Heekeren, K., … ENIGMA Clinical High Risk for Psychosis Working Group. (2023). Normative modeling of brain morphometry in Clinical High-Risk for Psychosis (No. 523348; BioRxiv). https://doi.org/10.1101/2023.01.17.523348
Abstract
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Importance: The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in the majority of individuals at psychosis risk may be nested within the range observed in healthy individuals.
Objective: To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high-risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with posi
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Haas, S. S., Ge, R., Agartz, I., Amminger, G. P., Andreassen, O. A., Bachman, P., Baeza, I., Choi, S., Colibazzi, T., Cropley, V. L., de la Fuente-Sandoval, C., Ebdrup, B. H., Fortea, A., Fusar-Poli, P., Glenthøj, B. Y., Glenthøj, L. B., Haut, K. M., Hayes, R. A., Heekeren, K., … ENIGMA Clinical High Risk for Psychosis Working Group. (2023). Normative modeling of brain morphometry in Clinical High-Risk for Psychosis (No. 523348; BioRxiv). https://doi.org/10.1101/2023.01.17.523348