Publication: Rapid homeostatic modulation of transsynaptic nanocolumn rings
Rapid homeostatic modulation of transsynaptic nanocolumn rings
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Muttathukunnel, P., Frei, P., Perry, S., Dickman, D., & Müller, M. (2022). Rapid homeostatic modulation of transsynaptic nanocolumn rings. Proceedings of the National Academy of Sciences of the United States of America, 119(45), e2119044119. https://doi.org/10.1073/pnas.2119044119
Abstract
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Abstract
Robust neural information transfer relies on a delicate molecular nano-architecture of chemical synapses. Neurotransmitter release is controlled by a specific arrangement of proteins within presynaptic active zones. How the specific presynaptic molecular architecture relates to postsynaptic organization and how synaptic nano-architecture is transsynaptically regulated to enable stable synaptic transmission remain enigmatic. Using time-gated stimulated emission-depletion microscopy at the Drosophila neuromuscular junction, we found tha
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- Muttathukunnel, Paola
- Frei, Patrick
- Perry, Sarah
- Dickman, Dion
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Muttathukunnel, P., Frei, P., Perry, S., Dickman, D., & Müller, M. (2022). Rapid homeostatic modulation of transsynaptic nanocolumn rings. Proceedings of the National Academy of Sciences of the United States of America, 119(45), e2119044119. https://doi.org/10.1073/pnas.2119044119
