Publication: The two subunits of the asialoglycoprotein receptor contain different sorting information.
The two subunits of the asialoglycoprotein receptor contain different sorting information.
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Fuhrer, C., Geffen, I., Huggel, K., & Spiess, M. (1994). The two subunits of the asialoglycoprotein receptor contain different sorting information. Journal of Biological Chemistry, 269(5), 3277–3282.
Abstract
Abstract
Abstract
The human asialoglycoprotein receptor, an endocytic transport receptor of the basolateral surface of hepatocytes, is a hetero-oligomer of two homologous subunits H1 and H2. The cytoplasmic domain of H1 has been shown previously to contain a tyrosine-based signal for endocytosis and basolateral sorting. Here, we have investigated sorting determinants within subunit H2 and their contribution to the targeting of the hetero-oligomeric receptor complex. Despite extensive sequence homology, H2 expressed separately in fibroblast cells was en
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- Geffen, I
- Huggel, K
- Spiess, M
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Citations
Fuhrer, C., Geffen, I., Huggel, K., & Spiess, M. (1994). The two subunits of the asialoglycoprotein receptor contain different sorting information. Journal of Biological Chemistry, 269(5), 3277–3282.
