Publication: Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT)
Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT)
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Grzmil, M., Boersema, P., Sharma, A., Blanc, A., Imobersteg, S., Pruschy, M., Picotti, P., Schibli, R., & Behe, M. (2022). Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT). Journal of Hematology & Oncology, 15, 123. https://doi.org/10.1186/s13045-022-01343-y
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The vast majority of our knowledge regarding cancer radiobiology and the activation of radioresistance mechanisms emerged from studies using external beam radiation therapy (EBRT). Yet, less is known about the cancer response to internal targeted radionuclide therapy (TRT). Our comparative phosphoproteomics analyzed cellular responses to TRT with lutetium-177-labeled minigastrin analogue [$^{177}$
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Grzmil, M., Boersema, P., Sharma, A., Blanc, A., Imobersteg, S., Pruschy, M., Picotti, P., Schibli, R., & Behe, M. (2022). Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT). Journal of Hematology & Oncology, 15, 123. https://doi.org/10.1186/s13045-022-01343-y