Publication: Iron phosphate nanoparticles for food fortification: Biological effects in rats and human cell lines
Iron phosphate nanoparticles for food fortification: Biological effects in rats and human cell lines
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von Moos, L. M., Schneider, M., Hilty, F. M., Hilbe, M., Arnold, M., Ziegler, N., Mato, D. S., Winkler, H., Tarik, M., Ludwig, C., Naegeli, H., Langhans, W., Zimmermann, M. B., Sturla, S. J., & Trantakis, I. A. (2017). Iron phosphate nanoparticles for food fortification: Biological effects in rats and human cell lines. Nanotoxicology, 11(4), 496–506. https://doi.org/10.1080/17435390.2017.1314035
Abstract
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Nanotechnology offers new opportunities for providing health benefits in foods. Food fortification with iron phosphate nanoparticles (FePO4 NPs) is a promising new approach to reducing iron deficiency because FePO4 NPs combine high bioavailability with superior sensory performance in difficult to fortify foods. However, their safety remains largely untested. We fed rats for 90 days diets containing FePO4 NPs at doses at which iron sulfate (FeSO4), a commonly used food fortificant, has been shown to induce adverse effects. Feeding did
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von Moos, L. M., Schneider, M., Hilty, F. M., Hilbe, M., Arnold, M., Ziegler, N., Mato, D. S., Winkler, H., Tarik, M., Ludwig, C., Naegeli, H., Langhans, W., Zimmermann, M. B., Sturla, S. J., & Trantakis, I. A. (2017). Iron phosphate nanoparticles for food fortification: Biological effects in rats and human cell lines. Nanotoxicology, 11(4), 496–506. https://doi.org/10.1080/17435390.2017.1314035