Publication: Ultrasound screening for chromosomal anomalies in the first trimester of pregnancy
Ultrasound screening for chromosomal anomalies in the first trimester of pregnancy
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Savoldelli, G., Binkert, F., Achermann, J., & Schmid, W. (1993). Ultrasound screening for chromosomal anomalies in the first trimester of pregnancy. Prenatal Diagnosis, 13(6), 513–518. https://doi.org/10.1002/pd.1970130613
Abstract
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Abstract
For the last 6 years, sonographic signs for excessive fluid accumulation in the backs of 10- to 12-week-old fetuses have been looked for prior to transabdominal chorionic biopsy. In 1400 pregnancies, subsequent karyotype analyses revealed 28 cases of Down syndrome. In 15 (= 54 per cent), a large fluid cushion over most of the back had been documented at the time of biopsy. Only a few chromosomally normal fetuses with the same peculiarity were observed. The cushion was also present in fetuses with trisomies 18 and 13, and in Turner syn
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- Savoldelli, Guido
- Binkert, Franz
- Achermann, Josef
- Schmid, Werner
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Savoldelli, G., Binkert, F., Achermann, J., & Schmid, W. (1993). Ultrasound screening for chromosomal anomalies in the first trimester of pregnancy. Prenatal Diagnosis, 13(6), 513–518. https://doi.org/10.1002/pd.1970130613