Publication: EMT 2.0: shaping epithelia through collective migration
EMT 2.0: shaping epithelia through collective migration
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Revenu, C., & Gilmour, D. (2009). EMT 2.0: shaping epithelia through collective migration. Current Opinion in Genetics & Development, 19(4), 338–342. https://doi.org/10.1016/j.gde.2009.04.007
Abstract
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Epithelial-mesenchymal transitions (EMTs) drive epithelial remodelling by converting cohesive, stable epithelial layers into individual, motile mesenchymal cells. It is now becoming clear that, from being an all-or-nothing switch, EMT can be applied in a fine-tuned manner to allow the efficient migration of cohesive epithelia that maintain their internal organisation. Recent work suggests that such collective motility involves a complex balance between epithelial and mesenchyme-like cell states that is driven by internal and external
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- Revenu, Céline
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Citations
Revenu, C., & Gilmour, D. (2009). EMT 2.0: shaping epithelia through collective migration. Current Opinion in Genetics & Development, 19(4), 338–342. https://doi.org/10.1016/j.gde.2009.04.007
