Publication: Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment
Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment
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Citations
Frese, L., Darwiche, S. E., von Rechenberg, B., Hoerstrup, S. P., Giovanoli, P., & Calcagni, M. (2021). Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment. Cytotherapy, 23, 536–547. https://doi.org/10.1016/j.jcyt.2021.01.006
Abstract
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BACKGROUND AIMS
Cultured patient-specific keratinocyte sheets have been used clinically since the 1970s for the treatment of large severe burns. However, despite significant developments in recent years, successful and sustainable treatment is still a challenge. Reliable, high-quality grafts with faster availability and a flexible time window for transplantation are required to improve clinical outcomes.
METHODS
Keratinocytes are usually grown in vitro at 37°C. Given the large temperature differences in native skin tissue, the aim
Additional indexing
Creators (Authors)
- Frese, Laura
- Darwiche, Salim E
- von Rechenberg, Brigitte
- Hoerstrup, Simon P
- Giovanoli, Pietro
- Calcagni, Maurizio
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Citations
Frese, L., Darwiche, S. E., von Rechenberg, B., Hoerstrup, S. P., Giovanoli, P., & Calcagni, M. (2021). Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment. Cytotherapy, 23, 536–547. https://doi.org/10.1016/j.jcyt.2021.01.006
