Publication: Amnion Cells in Tailored Hydrogels Deposit Human Amnion Native Extracellular Matrix
Amnion Cells in Tailored Hydrogels Deposit Human Amnion Native Extracellular Matrix
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Avilla-Royo, E., Roschitzki, B., Pfammatter, S., Grossmann, J., Airaghi, P., Vonzun, L., Ochsenbein‐Kölble, N., Vallmajo‐Martin, Q., & Ehrbar, M. (2022). Amnion Cells in Tailored Hydrogels Deposit Human Amnion Native Extracellular Matrix. Advanced Functional Materials, 32(40), 2204543. https://doi.org/10.1002/adfm.202204543
Abstract
Abstract
Abstract
Fetal therapies regularly result in iatrogenic preterm premature rupture of the fetal membranes (iPPROM), which is associated with preterm birth. Biomaterials that promote the healing of traumatized fetal membranes (FMs) may prevent iPPROM-associated preterm births, addressing this unmet clinical need. Here, a fully defined synthetic poly(ethylene glycol) (PEG) hydrogel is developed to study the healing functions of human amnion-derived mesenchymal stromal cells (hAMCs) in 3D cultures. A pipeline to analyze extracellular matrix (ECM)
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Creators (Authors)
- Avilla-Royo, Eva
- Roschitzki, Bernd
- Pfammatter, Sibylle
- Grossmann, Jonas
- Airaghi, Pietro
- Vonzun, Ladina
- Ochsenbein‐Kölble, Nicole
- Vallmajo‐Martin, Queralt
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Citations
Avilla-Royo, E., Roschitzki, B., Pfammatter, S., Grossmann, J., Airaghi, P., Vonzun, L., Ochsenbein‐Kölble, N., Vallmajo‐Martin, Q., & Ehrbar, M. (2022). Amnion Cells in Tailored Hydrogels Deposit Human Amnion Native Extracellular Matrix. Advanced Functional Materials, 32(40), 2204543. https://doi.org/10.1002/adfm.202204543
