Publication: Erythropoietin treatment leads to reduced blood glucose levels and body mass: Insights from murine models
Erythropoietin treatment leads to reduced blood glucose levels and body mass: Insights from murine models
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Katz, O., Stuible, M., Golishevski, N., Lifshitz, L., Tremblay, M., Gassmann, M., Mittelman, M., & Neumann, D. (2010). Erythropoietin treatment leads to reduced blood glucose levels and body mass: Insights from murine models. Journal of Endocrinology, 205(1), 87–95. https://doi.org/10.1677/JOE-09-0425
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Erythropoietin (EPO) regulates proliferation and differentiation of erythroid precursor cells into erythrocytes. The last decade has revealed non-renal sites of EPO production and extrahematopoietic expression of the EPO-receptor (EPO-R), thus suggesting that EPO has pleiotropic functions. Here we addressed the interplay between EPO / glucose metabolism / body weight, by employing a panel of relevant experimental murine models. The models focused on situations of increased EPO levels, including EPO injected C57BL/6 and BALB/c mice, as
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Katz, O., Stuible, M., Golishevski, N., Lifshitz, L., Tremblay, M., Gassmann, M., Mittelman, M., & Neumann, D. (2010). Erythropoietin treatment leads to reduced blood glucose levels and body mass: Insights from murine models. Journal of Endocrinology, 205(1), 87–95. https://doi.org/10.1677/JOE-09-0425