Publication: N-Ethyl-2-pyrrolidon (Dampf) [MAK Value Documentation in German language, 2016]
N-Ethyl-2-pyrrolidon (Dampf) [MAK Value Documentation in German language, 2016]
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Lohmann, R. D., Meischner, V., Leibold, E., Schriever-Schwemmer, G., Hartwig, A., MAK Commission, et al, & Arand, M. (2016). N-Ethyl-2-pyrrolidon (Dampf) [MAK Value Documentation in German language, 2016]. The MAK Collection for Occupational Health and Safety, 1, 209–218. https://doi.org/10.1002/3527600418.mb268791d0060
Abstract
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The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the work place (MAK value) of N‐ethyl‐2‐pyrrolidone of 2 ml/m3, considering the endpoints irritation of the respiratory tract and developmental toxicity.
The critical effect of N‐ethyl‐2‐pyrrolidone is degeneration of the olfactory epithelia in rats in a new 13‐week‐inhalation study. Since 2014, the Commission uses an empirical approach to set MAK values for substances with critical effect
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Lohmann, R. D., Meischner, V., Leibold, E., Schriever-Schwemmer, G., Hartwig, A., MAK Commission, et al, & Arand, M. (2016). N-Ethyl-2-pyrrolidon (Dampf) [MAK Value Documentation in German language, 2016]. The MAK Collection for Occupational Health and Safety, 1, 209–218. https://doi.org/10.1002/3527600418.mb268791d0060