Publication: Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria
Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria
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Stecher, B., Chaffron, S., Käppeli, R., Hapfelmeier, S., Freedrich, S., Weber, T. C., Kirundi, J., Suar, M., McCoy, K. D., von Mering, C., Macpherson, A. J., & Hardt, W. D. (2010). Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathogens, 6(1), e1000711. https://doi.org/10.1371/journal.ppat.1000711
Abstract
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Abstract
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The parameters defining whether this community permits invasion of a new bacterial species are unclear. In particular, inhibition of enteropathogen infection by the gut microbiota ( = colonization resistance) is poorly understood. To analyze the mechanisms of microbiota-mediated protection from Salmonella enterica induced enterocolitis, we used a mouse infection model and large scale high-throughput pyrosequencing. In contrast to convention
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- Stecher, B
- Chaffron, S
- Käppeli, R
- Hapfelmeier, S
- Freedrich, S
- Weber, T C
- Kirundi, J
- Suar, M
- McCoy, K D
- Macpherson, A J
- Hardt, W D
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Stecher, B., Chaffron, S., Käppeli, R., Hapfelmeier, S., Freedrich, S., Weber, T. C., Kirundi, J., Suar, M., McCoy, K. D., von Mering, C., Macpherson, A. J., & Hardt, W. D. (2010). Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. PLoS Pathogens, 6(1), e1000711. https://doi.org/10.1371/journal.ppat.1000711
