Publication: Immune cell populations and cytokine production in spleen and mesenteric lymph nodes after laparoscopic surgery versus conventional laparotomy in mice
Immune cell populations and cytokine production in spleen and mesenteric lymph nodes after laparoscopic surgery versus conventional laparotomy in mice
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Moehrlen, U., Lechner, A., Bäumel, M., Dostert, K., Röhrl, J., Meuli, M., Männel, D. N., & Hamacher, J. (2012). Immune cell populations and cytokine production in spleen and mesenteric lymph nodes after laparoscopic surgery versus conventional laparotomy in mice. Pediatric Surgery International, 28(5), 507–513. https://doi.org/10.1007/s00383-012-3070-1
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PURPOSE: There is evidence that open as well as minimally invasive abdominal surgery impair post-operative innate and acquired immune function. To compare the impact of these approaches as well as the one of different peritoneal gas exposures on immune function, we investigated cellular as well as cytokine-based immune parameters in mesenteric lymph nodes and the spleen postoperatively. METHODS: Mice (n = 26) were randomly assigned to the 4 study groups: (1) sham controls undergoing anesthesia alone, (2) laparotomy, and (3) air, or (4
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- Moehrlen, Ueli
- Lechner, Anja
- Bäumel, Monika
- Dostert, Karin
- Röhrl, Johann
- Meuli, Martin
- Männel, Daniela N
- Hamacher, Jürg
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Moehrlen, U., Lechner, A., Bäumel, M., Dostert, K., Röhrl, J., Meuli, M., Männel, D. N., & Hamacher, J. (2012). Immune cell populations and cytokine production in spleen and mesenteric lymph nodes after laparoscopic surgery versus conventional laparotomy in mice. Pediatric Surgery International, 28(5), 507–513. https://doi.org/10.1007/s00383-012-3070-1
