Publication: The breakup of intravascular microbubbles and its impact on the endothelium
The breakup of intravascular microbubbles and its impact on the endothelium
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Wiedemair, W., Tukovic, Z., Jasak, H., Poulikakos, D., & Kurtcuoglu, V. (2017). The breakup of intravascular microbubbles and its impact on the endothelium. Biomechanics and Modeling in Mechanobiology, 16, 611–624. https://doi.org/10.1007/s10237-016-0840-z
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Encapsulated microbubbles (MBs) serve as endovascular agents in a wide range of medical ultrasound applications. The oscillatory response of these agents to ultrasonic excitation is determined by MB size, gas content, viscoelastic shell properties and geometrical constraints. The viscoelastic parameters of the MB capsule vary during an oscillation cycle and change irreversibly upon shell rupture. The latter results in marked stress changes on the endothelium of capillary blood vessels due to altered MB dynamics. Mechanical effects on
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Wiedemair, W., Tukovic, Z., Jasak, H., Poulikakos, D., & Kurtcuoglu, V. (2017). The breakup of intravascular microbubbles and its impact on the endothelium. Biomechanics and Modeling in Mechanobiology, 16, 611–624. https://doi.org/10.1007/s10237-016-0840-z