Publication: To be dinuclear or not: Z-DNA induction by nickel complexes
To be dinuclear or not: Z-DNA induction by nickel complexes
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Spingler, B., & Antoni, P. M. (2007). To be dinuclear or not: Z-DNA induction by nickel complexes. Chemistry, 13(23), 6617–6622. https://doi.org/10.1002/chem.200600737
Abstract
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The left-handed Z-DNA has been identified as a gene regulating element. Therefore the generation of Z-DNA through metal complexes might be an innovative way for the regulation of gene expression. Use of the new dinuclear complex N,N,N',N'-tetrakis-2(3,5-dimethylpyrazol-1-yl)ethyl]-1,3- propylenediamine-bis(nickel(II) dinitrate) (2) reversibly induced Z-DNA formation. However, when a 1:1 ratio of metal/dinucleating ligand was used as a control, the midpoint of the B- to Z-DNA transition was at the same nickel concentration as in case o
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- Antoni, Philipp M
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Citations
Spingler, B., & Antoni, P. M. (2007). To be dinuclear or not: Z-DNA induction by nickel complexes. Chemistry, 13(23), 6617–6622. https://doi.org/10.1002/chem.200600737
