Publication: Collective cell migration guided by dynamically maintained gradients
Collective cell migration guided by dynamically maintained gradients
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Streichan, S. J., Valentin, G., Gilmour, D., & Hufnagel, L. (2011). Collective cell migration guided by dynamically maintained gradients. Physical Biology, 8(4), 045004. https://doi.org/10.1088/1478-3975/8/4/045004
Abstract
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How cell collectives move and deposit subunits within a developing embryo is a question of outstanding interest. In many cases, a chemotactic mechanism is employed, where cells move up or down a previously generated attractive or repulsive gradient of signalling molecules. Recent studies revealed the existence of systems with isotropic chemoattractant expression in the lateral line primordium of zebrafish. Here we propose a mechanism for a cell collective, which actively modulates an isotropically expressed ligand and encodes an initi
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- Streichan, Sebastian J
- Valentin, Guillaume
- Hufnagel, Lars
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Streichan, S. J., Valentin, G., Gilmour, D., & Hufnagel, L. (2011). Collective cell migration guided by dynamically maintained gradients. Physical Biology, 8(4), 045004. https://doi.org/10.1088/1478-3975/8/4/045004
