Functionalised Protein Conjugates for Applications in Molecular Imaging

Abstract

Modern medicine uses molecular imaging techniques to study biological processes at the tissue and subcellular levels. With use of molecular imaging, cancerous lesions can be diagnosed, and aspects of disease progression can be monitored. Oncological imaging requires appropriate targeting of biomarkers and hallmarks of cancer. Harnessing the high specificity of monoclonal antibodies and antibody mimetics for diagnostic imaging purposes, allows for specifically targeted tumour uptake with high contrast over healthy tissues. This thesis Show more