Publication: The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections
The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections
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De Neck, S., Penrice-Randal, R., Clark, J. J., Sharma, P., Bentley, E. G., Kirby, A., Mega, D. F., Han, X., Owen, A., Hiscox, J. A., Stewart, J. P., & Kipar, A. (2023). The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections. Viruses, 15(8), 1637. https://doi.org/10.3390/v15081637
Abstract
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Abstract
The respiratory system is the main target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 19 (COVID-19) where acute respiratory distress syndrome is considered the leading cause of death. Changes in pulmonary blood vessels, among which an endothelialitis/endotheliitis has been particularly emphasized, have been suggested to play a central role in the development of acute lung injury. Similar vascular changes are also observed in animal models of COVID-19. The present study aimed to det
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Creators (Authors)
- De Neck, Simon
- Penrice-Randal, Rebekah
- Clark, Jordan J
- Sharma, Parul
- Bentley, Eleanor G
- Kirby, Adam
- Mega, Daniele F
- Han, Ximeng
- Owen, Andrew
- Hiscox, Julian A
- Stewart, James P
- Kipar, Anja
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De Neck, S., Penrice-Randal, R., Clark, J. J., Sharma, P., Bentley, E. G., Kirby, A., Mega, D. F., Han, X., Owen, A., Hiscox, J. A., Stewart, J. P., & Kipar, A. (2023). The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections. Viruses, 15(8), 1637. https://doi.org/10.3390/v15081637
