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Insulin resistance and increased lipolysis in bone marrow derived adipocytes stimulated with agonists of Toll-like receptors

Date

Date

Date
2010
Journal Article
Published version

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Franchini, M., Monnais, E., Seboek, D., Radimerski, T., Zini, E., Kaufmann, K., Lutz, T. A., Reusch, C. E., Ackermann, M., Muller, B., & Linscheid, P. (2010). Insulin resistance and increased lipolysis in bone marrow derived adipocytes stimulated with agonists of Toll-like receptors. Hormone and Metabolic Research, 42(10), 703–709. https://doi.org/10.1055/s-0030-1261872

Abstract

Abstract

Abstract

Our objectives were to identify Toll-like receptors (TLRs) in human bone marrow derived adipocytes, to test specific TLR agonists for their ability to induce a proinflammatory response, and to investigate possible metabolic effects after TLR activation, in particular, those associated with insulin resistance and lipolysis. Mesenchymal stem cells were isolated from human bone marrow and differentiated into adipocytes. Total RNA before or after stimulation with agonists specific for TLR was extracted for analysis of expression of TLRs p

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2 since deposited on 2011-02-02
1last week
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

  • Franchini, M
    affiliation.icon.alt
  • Monnais, E
    affiliation.icon.alt
  • Seboek, D
    affiliation.icon.alt
  • Radimerski, T
    affiliation.icon.alt
  • Zini, Eric
    affiliation.icon.alt
  • Kaufmann, K
    affiliation.icon.alt
  • Reusch, Claudia E
    affiliation.icon.alt
  • Ackermann, Mathias
    affiliation.icon.alt
  • Muller, B
    affiliation.icon.alt
  • Linscheid, P
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
42

Number

Number

Number
10

Page range/Item number

Page range/Item number

Page range/Item number
703

Page end

Page end

Page end
709

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2010

Date available

Date available

Date available
2011-02-02

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Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0018-5043

OA Status

OA Status

OA Status
Closed

PubMed ID

PubMed ID

PubMed ID

Metrics

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2 since deposited on 2011-02-02
1last week
Acq. date: 2025-11-12

Citations

Citation copied

Franchini, M., Monnais, E., Seboek, D., Radimerski, T., Zini, E., Kaufmann, K., Lutz, T. A., Reusch, C. E., Ackermann, M., Muller, B., & Linscheid, P. (2010). Insulin resistance and increased lipolysis in bone marrow derived adipocytes stimulated with agonists of Toll-like receptors. Hormone and Metabolic Research, 42(10), 703–709. https://doi.org/10.1055/s-0030-1261872

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