Publication: Evidence base for restrictive transfusion triggers in high-risk patients
Evidence base for restrictive transfusion triggers in high-risk patients
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Spahn, D. R., Spahn, G. H., & Stein, P. (2015). Evidence base for restrictive transfusion triggers in high-risk patients. Transfusion Medicine and Hemotherapy, 42, 110–114. https://doi.org/10.1159/000381509
Abstract
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Abstract
Liberal versus restrictive red blood cell (RBC) transfusion triggers have been debated for years. This review illustrates the human body's physiologic response to acute anemia and summarizes the evidence from prospective randomized trials (RCTs) for restrictive use of RBC transfusions in high-risk patients. During progressive anemia, the human body maintains the oxygen delivery to the tissues by an increase in cardiac output and peripheral oxygen extraction. Seven RCTs with a total of 5,566 high-risk patients compared a restrictive he
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- Spahn, Donat R
- Spahn, Gabriela H
- Stein, Philipp
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Spahn, D. R., Spahn, G. H., & Stein, P. (2015). Evidence base for restrictive transfusion triggers in high-risk patients. Transfusion Medicine and Hemotherapy, 42, 110–114. https://doi.org/10.1159/000381509
