Publication: Cartilage/bone interface fabricated under perfusion: Spatially organized commitment of adipose-derived stem cells without medium supplementation
Cartilage/bone interface fabricated under perfusion: Spatially organized commitment of adipose-derived stem cells without medium supplementation
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Baumgartner, W., Otto, L., Hess, S. C., Stark, W. J., Märsmann, S., Bürgisser, G. M., Calcagni, M., Cinelli, P., & Buschmann, J. (2019). Cartilage/bone interface fabricated under perfusion: Spatially organized commitment of adipose-derived stem cells without medium supplementation. Journal of Biomedical Materials Research. Part B, 107(6), 1833–1843. https://doi.org/10.1002/jbm.b.34276
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Tissue engineering of an osteochondral interface demands for a gradual transition of chondrocyte- to osteoblast-prevailing tissue. If stem cells are used as a single cell source, an appropriate cue to trigger the desired differentiation is the use of composite materials with different amounts of calcium phosphate. Electrospun meshes of poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles (PLGA/aCaP) in weight ratios of 100:0; 90:10, 80:20, and 70:30 were seeded with human adipose-derived stem cells (ASCs) and cul
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- Baumgartner, Walter
- Otto, Lukas
- Hess, Samuel C
- Stark, Wendelin J
- Märsmann, Sonja
- Bürgisser, Gabriella Meier
- Calcagni, Maurizio
- Cinelli, Paolo
- Buschmann, Johanna
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Baumgartner, W., Otto, L., Hess, S. C., Stark, W. J., Märsmann, S., Bürgisser, G. M., Calcagni, M., Cinelli, P., & Buschmann, J. (2019). Cartilage/bone interface fabricated under perfusion: Spatially organized commitment of adipose-derived stem cells without medium supplementation. Journal of Biomedical Materials Research. Part B, 107(6), 1833–1843. https://doi.org/10.1002/jbm.b.34276