Publication: Rapid functional reorganization of sensory-motor cortex after thoracic spinal cord injury in adult rats
Rapid functional reorganization of sensory-motor cortex after thoracic spinal cord injury in adult rats
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Sydekum, E., Ghosh, A., Gullo, M., Baltes, C., Schwab, M. E., & Rudin, M. (2013). Rapid functional reorganization of sensory-motor cortex after thoracic spinal cord injury in adult rats. NeuroImage, 87, 72–79. https://doi.org/10.1016/j.neuroimage.2013.10.045
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Thoracic spinal cord injured rats rely largely on forelimbs to walk, as their hindlimbs are dysfunctional. This increased limb use is accompanied by expansion of the cortical forelimb sensory representation. It is unclear how quickly the representational changes occur and whether they are at all related to the behavioral adaptation. Using blood oxygenation level dependent functional mangetic resonance imaging (BOLD-fMRI) we show that major plastic changes of the somato-sensory map can occur as early as one day after injury. The extent
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- Sydekum, E
- Ghosh, A
- Gullo, M
- Baltes, C
- Rudin, M
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Sydekum, E., Ghosh, A., Gullo, M., Baltes, C., Schwab, M. E., & Rudin, M. (2013). Rapid functional reorganization of sensory-motor cortex after thoracic spinal cord injury in adult rats. NeuroImage, 87, 72–79. https://doi.org/10.1016/j.neuroimage.2013.10.045