Publication: Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders
Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders
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Heimer, J., Gascho, D., Madea, B., Steuer, A. E., Martinez, R. M., Thali, M. J., & Zoelch, N. (2020). Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders. International Journal of Legal Medicine, 134(2), 603–612. https://doi.org/10.1007/s00414-019-02235-6
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Purpose: The detection and quantification of metabolites relevant for the diagnosis of fatal metabolic disorders by proton magnetic resonance spectroscopy (1H-MRS) was recently demonstrated. This prospective study aimed to compare the concentrations of beta-hydroxybutyrate (BHB), glucose (GLC), and lactate (LAC) derived from both biochemical analyses and 1H-MRS for the diagnosis of fatal metabolic disorders. Methods: In total, 20 cases with suspected fatal metabolic disorders were included in the study. For the agreement based on thre
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- Heimer, Jakob
- Gascho, Dominic
- Madea, Burkhard
- Steuer, Andrea E
- Martinez, Rosa Maria
- Thali, Michael J
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Heimer, J., Gascho, D., Madea, B., Steuer, A. E., Martinez, R. M., Thali, M. J., & Zoelch, N. (2020). Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders. International Journal of Legal Medicine, 134(2), 603–612. https://doi.org/10.1007/s00414-019-02235-6
