Publication: Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
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Erlebach, R., Buhlmann, A., Andermatt, R., Seeliger, B., Stahl, K., Bode, C., Schüpbach, R., Wendel-Garcia, P. D., David, S., Kleinert, E.-M., Hofmaenner, D. A., Müller, M. M., Ganter, C. C., Welte, T., Pape, T., Rath, A.-K., Nalbant, B., Ruwisch, J., Putensen, C., … Wild, L. (2024). Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 12, 41. https://doi.org/10.1186/s40635-024-00626-7
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Background The continuous exposure of blood to a non-biological surface during extracorporeal membrane oxygenation (ECMO) may lead to progressive thrombus formation in the oxygenator, hemolysis and consequently impaired gas exchange. In most centers oxygenator performance is monitored only on a once daily basis. Carboxyhemoglobin (COHb) is generated upon red cell lysis and is routinely measured with any co-oximetry performed to surveille gas exchange and acid–base homeostasis every couple of hours. This retrospective cohort study aim
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- Erlebach, Rolf
- Buhlmann, Alix
- Andermatt, Rea
- Seeliger, Benjamin
- Stahl, Klaus
- Bode, Christian
- Wendel-Garcia, Pedro David
- David, Sascha
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Erlebach, R., Buhlmann, A., Andermatt, R., Seeliger, B., Stahl, K., Bode, C., Schüpbach, R., Wendel-Garcia, P. D., David, S., Kleinert, E.-M., Hofmaenner, D. A., Müller, M. M., Ganter, C. C., Welte, T., Pape, T., Rath, A.-K., Nalbant, B., Ruwisch, J., Putensen, C., … Wild, L. (2024). Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 12, 41. https://doi.org/10.1186/s40635-024-00626-7
