Aufgrund des stetig wachsenden Drucks - ausgelöst von automatisiertem Datenverkehr (z.B. Bots, Crawler und DDoS-Attacken) - sind unsere Server immer öfter so ausgelastet, dass ZORA nicht mehr erreichbar ist. Dies wird weltweit von weiteren Repositorien berichtet. Wir arbeiten unter Hochdruck daran, wenigstens den UZH-Mitgliedern Zugriff zu bieten über das UZH-Netzwerk oder VPN. Danke für Ihre Geduld.

Due to the ever-increasing pressure caused by automated data traffic (e.g., bots, crawlers, and DDoS attacks), our servers are increasingly overloaded, making ZORA inaccessible. This has been reported by other repositories around the world. We are working around the clock to ensure that at least UZH members can access the platform via the UZH network or VPN. Thank you for your patience.

 

Publication:

Five challenges in evolution and infectious diseases

Date

Date

Date
2015
Journal Article
Published version
Simple data Full metadata Statistics
cris.lastimport.scopus2025-08-10T03:33:54Z
cris.lastimport.wos2025-08-14T01:32:58Z
dc.contributor.institutionUniversity of Zurich
dc.date.accessioned2016-02-22T10:43:39Z
dc.date.available2016-02-22T10:43:39Z
dc.date.issued2015-03
dc.description.abstract

Evolution is a key aspect of the biology of many pathogens, driving processes ranging from immune escape to changes in virulence. Because evolution is inherently subject to feedbacks, and because pathogen evolution plays out at scales ranging from within-host to between-host and beyond, evolutionary questions provide special challenges to the modelling community. In this article, we provide an overview of five challenges in modelling the evolution of pathogens and their hosts, and point to areas for development, focussing in particular on the issue of linking theory and data.

dc.identifier.doi10.1016/j.epidem.2014.12.003
dc.identifier.issn1878-0067
dc.identifier.scopus2-s2.0-84939946261
dc.identifier.urihttps://www.zora.uzh.ch/handle/20.500.14742/118140
dc.identifier.wos000352226900010
dc.language.isoeng
dc.subject.ddc610 Medicine & health
dc.title

Five challenges in evolution and infectious diseases

dc.typearticle
dcterms.accessRightsinfo:eu-repo/semantics/openAccess
dcterms.bibliographicCitation.journaltitleEpidemics
dcterms.bibliographicCitation.originalpublishernameElsevier
dcterms.bibliographicCitation.pageend44
dcterms.bibliographicCitation.pagestart40
dcterms.bibliographicCitation.pmid25843381
dcterms.bibliographicCitation.volume10
dspace.entity.typePublicationen
uzh.contributor.affiliationPrinceton University, National Institutes of Health, Bethesda
uzh.contributor.affiliationPrinceton University
uzh.contributor.affiliationLondon School of Hygiene & Tropical Medicine
uzh.contributor.affiliationUniversitatsSpital Zurich
uzh.contributor.affiliationNational Institutes of Health, Bethesda, University of California, Los Angeles
uzh.contributor.affiliationQueen Mary, University of London
uzh.contributor.authorMetcalf, C J E
uzh.contributor.authorBirger, R B
uzh.contributor.authorFunk, S
uzh.contributor.authorKouyos, R D
uzh.contributor.authorLloyd-Smith, J O
uzh.contributor.authorJansen, V A A
uzh.contributor.correspondenceYes
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.contributor.correspondenceNo
uzh.document.availabilitypublished_version
uzh.eprint.datestamp2016-02-22 10:43:39
uzh.eprint.lastmod2025-08-14 01:40:06
uzh.eprint.statusChange2016-02-22 10:43:39
uzh.harvester.ethYes
uzh.harvester.nbNo
uzh.identifier.doi10.5167/uzh-122259
uzh.jdb.eprintsId21462
uzh.oastatus.unpaywallgold
uzh.oastatus.zoraGold
uzh.publication.citationMetcalf, C. J. E., Birger, R. B., Funk, S., Kouyos, R. D., Lloyd-Smith, J. O., & Jansen, V. A. A. (2015). Five challenges in evolution and infectious diseases. Epidemics, 10, 40–44. https://doi.org/10.1016/j.epidem.2014.12.003
uzh.publication.freeAccessAtdoi
uzh.publication.originalworkfurther
uzh.publication.publishedStatusfinal
uzh.scopus.impact33
uzh.scopus.subjectsParasitology
uzh.scopus.subjectsEpidemiology
uzh.scopus.subjectsMicrobiology
uzh.scopus.subjectsPublic Health, Environmental and Occupational Health
uzh.scopus.subjectsVirology
uzh.scopus.subjectsInfectious Diseases
uzh.workflow.doajuzh.workflow.doaj.true
uzh.workflow.eprintid122259
uzh.workflow.fulltextStatuspublic
uzh.workflow.revisions49
uzh.workflow.rightsCheckkeininfo
uzh.workflow.statusarchive
uzh.wos.impact28
Files

Original bundle

Name:
1-s2.0-S1755436514000723-main.pdf
Size:
647.34 KB
Format:
Adobe Portable Document Format
1-s2.0-S1755436514000723-main.pdfview fileDownload |Download647.34 KB
Publication available in collections:
Publications of Clinic for Infectious Diseases