Publication: Survival analysis of dogs with advanced primary lung carcinoma treated by metronomic cyclophosphamide, piroxicam and thalidomide
Survival analysis of dogs with advanced primary lung carcinoma treated by metronomic cyclophosphamide, piroxicam and thalidomide
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Polton, G., Finotello, R., Sabattini, S., Rossi, F., Laganga, P., Vasconi, M. E., Barbanera, A., Stiborova, K., Rohrer Bley, C., & Marconato, L. (2018). Survival analysis of dogs with advanced primary lung carcinoma treated by metronomic cyclophosphamide, piroxicam and thalidomide. Veterinary and Comparative Oncology, 16(3), 399–408. https://doi.org/10.1111/vco.12393
Abstract
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Abstract
Unresectable or metastatic (advanced) primary pulmonary carcinoma (PPC) represents a therapeutic challenge where surgery may be contraindicated and the therapeutic role of maximum-tolerated dose (MTD) chemotherapy remains uncertain. This study was undertaken to explore the impact of metronomic chemotherapy (MC) in dogs with advanced PPC. Previously untreated dogs with advanced (T3 or N1 or M1) PPC, with complete staging work-up and follow-up data, receiving MC (comprising low-dose cyclophosphamide, piroxicam and thalidomide), surgery,
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Polton, G., Finotello, R., Sabattini, S., Rossi, F., Laganga, P., Vasconi, M. E., Barbanera, A., Stiborova, K., Rohrer Bley, C., & Marconato, L. (2018). Survival analysis of dogs with advanced primary lung carcinoma treated by metronomic cyclophosphamide, piroxicam and thalidomide. Veterinary and Comparative Oncology, 16(3), 399–408. https://doi.org/10.1111/vco.12393