Publication: The genes for the highly homologous Ca2+-binding proteins oncomodulin and parvalbumin are not linked in the human genome
The genes for the highly homologous Ca2+-binding proteins oncomodulin and parvalbumin are not linked in the human genome
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Ritzler, J. M., Sawhney, R., Geurts van Kessei, A. H. M., Grzeschik, K.-H., Schinzel, A., & Berchtold, M. W. (1992). The genes for the highly homologous Ca2+-binding proteins oncomodulin and parvalbumin are not linked in the human genome. Genomics, 12, 567–572. https://doi.org/10.1016/0888-7543(92)90449-3
Abstract
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Abstract
The chromosomal loci of the human parvalbumin and oncomodulin single-copy genes that encode structurally and evolutionarily closely related Ca(2+)-binding proteins were determined by somatic cell hybrid analysis. Southern blot analysis of genomic DNA from 25 human-hamster somatic cell hybrids showed that the human gene for oncomodulin resides on chromosome 7. Analysis of human-mouse hybrids selectively retaining human chromosome 7 or a portion of it allowed specific assignment of the gene locus to the p11-p13 region of chromosome 7 kn
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- Ritzler, J M
- Sawhney, R
- Geurts van Kessei, A H M
- Grzeschik, K -H
- Schinzel, Albert
- Berchtold, M W
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Ritzler, J. M., Sawhney, R., Geurts van Kessei, A. H. M., Grzeschik, K.-H., Schinzel, A., & Berchtold, M. W. (1992). The genes for the highly homologous Ca2+-binding proteins oncomodulin and parvalbumin are not linked in the human genome. Genomics, 12, 567–572. https://doi.org/10.1016/0888-7543(92)90449-3
