Publication: Is small fiber neuropathy induced by gadolinium-based contrast agents?
Is small fiber neuropathy induced by gadolinium-based contrast agents?
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Radbruch, A., Richter, H., Bücker, P., Berlandi, J., Schänzer, A., Deike-Hofmann, K., Kleinschnitz, C., Schlemmer, H.-P., Forsting, M., Paulus, W., Martin, L. F., van Thriel, C., Karst, U., & Jeibmann, A. (2020). Is small fiber neuropathy induced by gadolinium-based contrast agents? Investigative Radiology, 55, 473–480. https://doi.org/10.1097/RLI.0000000000000677
Abstract
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OBJECTIVES: In recent years, complaints of patients about burning pain in arms and legs after the injection of gadolinium-based contrast agents (GBCAs) have been reported. In the current study, we investigated changes of small fibers in the epidermis as a potential cause of the patient complaints in a mouse model. METHODS: Six groups of 8 mice were intravenously injected with either a macrocyclic GBCA (gadoteridol, gadoterate meglumine, gadobutrol), a linear GBCA (gadodiamide or gadobenate dimeglumine) (1 mmol/kg body weight), or sali
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Creators (Authors)
- Radbruch, Alexander
- Richter, Henning
- Bücker, Patrick
- Berlandi, Johannes
- Schänzer, Anne
- Deike-Hofmann, Katerina
- Kleinschnitz, Christoph
- Schlemmer, Heinz-Peter
- Forsting, Michael
- Paulus, Werner
- Martin, Louise F
- van Thriel, Christoph
- Karst, Uwe
- Jeibmann, Astrid
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Radbruch, A., Richter, H., Bücker, P., Berlandi, J., Schänzer, A., Deike-Hofmann, K., Kleinschnitz, C., Schlemmer, H.-P., Forsting, M., Paulus, W., Martin, L. F., van Thriel, C., Karst, U., & Jeibmann, A. (2020). Is small fiber neuropathy induced by gadolinium-based contrast agents? Investigative Radiology, 55, 473–480. https://doi.org/10.1097/RLI.0000000000000677
