Publication: Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin.
Date
Date
Date
Citations
Oldham, S., Montagne, J., Radimerski, T., Thomas, G., & Hafen, E. (2000). Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes and Development, 14(21), 2689–2694. https://doi.org/10.1101/gad.845700
Abstract
Abstract
Abstract
The adaptation of growth in response to nutritional changes is essential for the proper development of all organisms. Here we describe the identification of the Drosophila homolog of the target of rapamycin (TOR), a candidate effector for nutritional sensing. Genetic and biochemical analyses indicate that dTOR impinges on the insulin signaling pathway by autonomously affecting growth through modulating the activity of dS6K. However, in contrast to other components in the insulin signaling pathway, partial loss of dTOR function prefere
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Oldham, S
- Montagne, J
- Radimerski, T
- Thomas, G
- Hafen, E
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Oldham, S., Montagne, J., Radimerski, T., Thomas, G., & Hafen, E. (2000). Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes and Development, 14(21), 2689–2694. https://doi.org/10.1101/gad.845700
